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Medicines and reduced kidney function

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People with reduced kidney function are at increased risk of experiencing medicine related harm. Reduced kidney function is a major risk factor for serious adverse drug reactions and is associated with poor outcomes include reduced quality of life, hospital admissions and death.1 In Australia, 1 in 3 people with reduced kidney function are prescribed medicines that are either inappropriately high doses or contraindicated due to kidney function.2 

 

The below resources and activities have been designed to assist pharmacists utilise medicine considerations as well as the specific patient and disease related considerations, to formulate appropriate dosing adjustment recommendations for those with reduce kidney function.  

Resources and activities

References: 

1. Laville S, Gras-Champel V, Hamroun A, Moragny J, Lambert O, Metzger M, et al. Kidney Function Decline and Serious Adverse Drug Reactions in Patients With CKD. Am J Kidney Dis. 2024;83(5):601-14. 

 

2. Castelino R, Saunder T, Kitsos A, Peterson G, Jose M, Wimmer B, et al. Quality use of medicines in patients with chronic kidney disease. BMC Nephrol. 2020;21(1):216. 

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